Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata

Many genetic factors that contribute to uterine leiomyomata (UL) - the most common tumours of the female genital tract - remain to be discovered. Here, the authors conduct a UL meta-genome-wide association study, and find loci related to altered muscle tissue biology that are associated with UL.

Bibliographic Details
Main Authors: Eeva Sliz, Jaakko S. Tyrmi, Nilufer Rahmioglu, Krina T. Zondervan, Christian M. Becker, FinnGen, Outi Uimari, Johannes Kettunen
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-35974-7