Activity of the growth hormone‐releasing hormone antagonist MIA602 and its underlying mechanisms of action in sarcoidosis‐like granuloma

Activity of the growth hormone‐releasing hormone antagonist MIA602 and its underlying mechanisms of action in sarcoidosis‐like granuloma

Abstract Objectives Growth hormone‐releasing hormone (GHRH) is a potent stimulator of growth hormone (GH) secretion from the pituitary gland. Although GHRH is essential for the growth of immune cells, the regulatory effects of its antagonist in granulomatous disease remain unknown. Methods Here, we...

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Bibliographic Details
Main Authors: Chongxu Zhang, Runxia Tian, Emilee M Dreifus, Abdolrazagh Hashemi Shahraki, Gregory Holt, Renzhi Cai, Anthony Griswold, Pablo Bejarano, Robert Jackson, Andrew V Schally, Mehdi Mirsaeidi
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
GHRH antagonist
granuloma
MIA602
sarcoidosis
Online Access:https://doi.org/10.1002/cti2.1310

Internet

https://doi.org/10.1002/cti2.1310

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