A Mass Spectrometry Based Metabolite Profiling Workflow for Selecting Abundant Specific Markers and Their Structurally Related Multi-Component Signatures in Traditional Chinese Medicine Multi‐Herb Formulae

A Mass Spectrometry Based Metabolite Profiling Workflow for Selecting Abundant Specific Markers and Their Structurally Related Multi-Component Signatures in Traditional Chinese Medicine Multi‐Herb Formulae

In Traditional Chinese Medicine (TCM), herbal preparations often consist of a mixture of herbs. Their quality control is challenging because every single herb contains hundreds of components (secondary metabolites). A typical 10 herb TCM formula was selected to develop an innovative strategy for its...

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Bibliographic Details
Main Authors: Joëlle Houriet, Pierre-Marie Allard, Emerson Ferreira Queiroz, Laurence Marcourt, Arnaud Gaudry, Lennie Vallin, Songhua Li, Yu Lin, Ruwei Wang, Kenny Kuchta, Jean-Luc Wolfender
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Pharmacology
Subjects:
multi-herb formulae
Traditional Chinese Medicine
feature-based molecular network
quality control
multi-component signature, TCM, Mass spectrometry, Chemical markers
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.578346/full

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https://www.frontiersin.org/articles/10.3389/fphar.2020.578346/full

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