Rutin pretreatment promotes microglial M1 to M2 phenotype polarization

Rutin pretreatment promotes microglial M1 to M2 phenotype polarization

Microglial cells are important resident innate immune components in the central nervous system that are often activated during neuroinflammation. Activated microglia can display one of two phenotypes, M1 or M2, which each play distinct roles in neuroinflammation. Rutin, a dietary flavonoid, exhibits...

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Bibliographic Details
Main Authors: Guang-Ping Lang, Can Li, Ying-Ying Han
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
bv-2 cells; flavonoid; m1 microglia; m2 microglia; microglia activation; microglia polarization; neuroinflammation; proinflammatory cytokines; rutin; tlr-4 signaling
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=12;spage=2499;epage=2504;aulast=Lang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=12;spage=2499;epage=2504;aulast=Lang

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