Integrative modeling of lncRNA-chromatin interaction maps reveals diverse mechanisms of nuclear retention

Integrative modeling of lncRNA-chromatin interaction maps reveals diverse mechanisms of nuclear retention

Abstract Background Many long non-coding RNAs, known to be involved in transcriptional regulation, are enriched in the nucleus and interact with chromatin. However, their mechanisms of chromatin interaction and the served cellular functions are poorly understood. We sought to characterize the mechan...

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Bibliographic Details
Main Authors: Shayan Tabe-Bordbar, Saurabh Sinha
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Genomics
Subjects:
Long non-coding RNA
Nuclear localization
Chromatin interaction
DNA Damage Response
R-loop
Machine learning
Online Access:https://doi.org/10.1186/s12864-023-09498-9

Internet

https://doi.org/10.1186/s12864-023-09498-9

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