Evaluation of novel epibatidine analogs in the rat nicotine drug discrimination assay and in the rat chronic constriction injury neuropathic pain model

Nicotine is the primary psychoactive component responsible for maintaining tobacco dependence in humans. Chronic pain is often a consequence of tobacco-related pathologies, and the development of a dual therapeutic that could treat chronic pain and tobacco dependence would be advantageous. Epibatidi...

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Bibliographic Details
Main Authors: Kevin Luque-Sanchez, Jasmine Felix, Joshua Bilbrey, Luis Restrepo, Morgan Reeves, Lance R. McMahon, Jenny L. Wilkerson
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Advances in Drug and Alcohol Research
Subjects:
Online Access:https://www.frontierspartnerships.org/articles/10.3389/adar.2023.11622/full