Genetic Mouse Models to Study Pancreatic Cancer-Induced Pain and Reduction in Well-Being

In addition to the poor prognosis, excruciating abdominal pain is a major challenge in pancreatic cancer. Neurotropism appears to be the underlying mechanism leading to neuronal invasion. However, there is a lack of animal models suitable for translationally bridging in vitro findings with clinical...

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Bibliographic Details
Main Authors: Michael Hirth, Yong Xie, Christiane Höper, Amandine Prats, Thilo Hackert, Matthias P. Ebert, Rohini Kuner
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/17/2634