SARS-CoV-2 nonstructural protein 6 from Alpha to Omicron: evolution of a transmembrane protein

ABSTRACT We recently reported that mutations in both the spike glycoprotein and nonstructural protein 6 (nsp6) were associated with attenuation of the SARS-CoV-2 Omicron BA.1 variant. While mutations in spike allow evasion of neutralizing antibodies and promote specific modes of viral entry, the rol...

Full description

Bibliographic Details
Main Authors: Shuchen Feng, Amornrat O'Brien, Da-Yuan Chen, Mohsan Saeed, Susan C. Baker
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.00688-23