Electrophysiological and Neurochemical Considerations of Distinct Neuronal Populations in the Rat Pedunculopontine Nucleus and Their Responsiveness Following 6-Hydroxydopamine Lesions

Electrophysiological and Neurochemical Considerations of Distinct Neuronal Populations in the Rat Pedunculopontine Nucleus and Their Responsiveness Following 6-Hydroxydopamine Lesions

The pedunculopontine nucleus (PPN) is composed of a morphologically and neurochemically heterogeneous population of neurons, which is severely affected by Parkinson’s disease (PD). However, the role of each subtype of neurons within the PPN in the pathophysiology of PD has not been completely elucid...

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Bibliographic Details
Main Authors: Xuenan Wang, Xiwen Geng, Min Li, Jinlu Xie, Dadian Chen, Hongyu Han, Xiaoqian Meng, Xiaomeng Yao, Haiyan Zhang, Yunfeng Gao, Hongli Chang, Xiao Zhang, Yanan Wang, Min Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neuroscience
Subjects:
pedunculopontine nucleus
Parkinson’s disease
firing pattern
synchronization
morphology
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01034/full

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https://www.frontiersin.org/article/10.3389/fnins.2019.01034/full

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