Does Proton Pump Inhibitors Decrease the Efficacy of Palbociclib and Ribociclib in Patients with Metastatic Breast Cancer?

Does Proton Pump Inhibitors Decrease the Efficacy of Palbociclib and Ribociclib in Patients with Metastatic Breast Cancer?

<i>Background and Objectives:</i> This investigation aimed to determine the impacts of concurrent proton pump inhibitors (PPIs) on progression-free survival (PFS) in patients with hormone receptor-positive and HER2-negative metastatic breast cancer managed with palbociclib or ribociclib...

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Bibliographic Details
Main Authors: Hatice Odabas, Akif Dogan, Melike Ozcelik, Sedat Yildirim, Ugur Ozkerim, Nedim Turan, Mahmut Emre Yildirim, Mahmut Gumus
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Medicina
Subjects:
metastatic breast cancer
palbociclib
ribociclib
proton pump inhibitors
drug-drug interactions
Online Access:https://www.mdpi.com/1648-9144/59/3/557

Internet

https://www.mdpi.com/1648-9144/59/3/557

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