Qualification of a flow cytometry-based method for the evaluation of in vitro cytotoxicity of GTA002 natural killer cell therapy

Qualification of a flow cytometry-based method for the evaluation of in vitro cytotoxicity of GTA002 natural killer cell therapy

Background: Natural Killer (NK) cell-based therapies represent a ground-breaking opportunity for the treatment of solid tumors and hematological malignancies. NK cell manufacturing under good manufacturing practice (GMP) is complex and requires attentive assessment the product's safety and effi...

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Bibliographic Details
Main Authors: Monica Raimo, Alexandra G. Zavoianu, Wilma Meijs, Pascal Scholten, Jan Spanholtz
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
ATMP
Flow cytometry
Immunotherapy
Method qualification
Method validation
Quality control
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024007461

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http://www.sciencedirect.com/science/article/pii/S2405844024007461

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