Cancer Biogenesis in Ribosomopathies

Ribosomopathies are congenital diseases with defects in ribosome assembly and are characterized by elevated cancer risks. Additionally, somatic mutations in ribosomal proteins have recently been linked to a variety of cancers. Despite a clear correlation between ribosome defects and cancer, the mole...

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Bibliographic Details
Main Authors: Sergey O. Sulima, Kim R. Kampen, Kim De Keersmaecker
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/8/3/229