Isolation, Characterization, Complete Structural Assignment, and Anticancer Activities of the Methoxylated Flavonoids from <i>Rhamnus disperma</i> Roots

Isolation, Characterization, Complete Structural Assignment, and Anticancer Activities of the Methoxylated Flavonoids from <i>Rhamnus disperma</i> Roots

Different chromatographic methods including reversed-phase HPLC led to the isolation and purification of three <i>O</i>-methylated flavonoids; 5,4’-dihydroxy-3,6,7-tri-<i>O</i>-methyl flavone (penduletin) (<b>1</b>), 5,3’-dihydroxy-3,6,7,4’,5’-penta-<i>O<...

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Bibliographic Details
Main Authors: Hamdoon A. Mohammed, Mohammed F. Abd El-Wahab, Usama Shaheen, Abd El-Salam I. Mohammed, Ashraf N. Abdalla, Ehab A. Ragab
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
<i>Rhamnus disperma</i>
flavonoids
methoxylated flavonoids
cytotoxicity
apoptosis
cell cycle
Online Access:https://www.mdpi.com/1420-3049/26/19/5827

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https://www.mdpi.com/1420-3049/26/19/5827

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