Targeting chromosome trisomy for chromosome editing

Abstract A trisomy is a type of aneuploidy characterised by an additional chromosome. The additional chromosome theoretically accepts any kind of changes since it is not necessary for cellular proliferation. This advantage led us to apply two chromosome manipulation methods to autosomal trisomy in c...

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Bibliographic Details
Main Authors: Takuya Abe, Yuya Suzuki, Teppei Ikeya, Kouji Hirota
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97580-1