Myelodysplastic Syndromes in the Postgenomic Era and Future Perspectives for Precision Medicine

Myelodysplastic Syndromes in the Postgenomic Era and Future Perspectives for Precision Medicine

Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal disorders caused by sequential accumulation of somatic driver mutations in hematopoietic stem and progenitor cells (HSPCs). MDS is characterized by ineffective hematopoiesis with cytopenia, dysplasia, inflammation, and a varia...

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Bibliographic Details
Main Authors: Ioannis Chanias, Kristina Stojkov, Gregor Th. Stehle, Michael Daskalakis, Helena Simeunovic, Linet Muthoni Njue, Annatina S. Schnegg-Kaufmann, Naomi A. Porret, Ramanjaneyulu Allam, Tata Nageswara Rao, Rudolf Benz, Axel Ruefer, Adrian Schmidt, Marcel Adler, Alicia Rovo, Stefan Balabanov, Georg Stuessi, Ulrike Bacher, Nicolas Bonadies
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
myelodysplastic syndromes
postgenomic era
precision medicine
targeted therapies
future perspectives
Online Access:https://www.mdpi.com/2072-6694/13/13/3296

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https://www.mdpi.com/2072-6694/13/13/3296

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