Efficacy and safety of PARP inhibitors combined with antiangiogenic agents in the maintenance treatment of ovarian cancer: a systematic review and meta-analysis with trial sequential analysis of randomized controlled trials

Efficacy and safety of PARP inhibitors combined with antiangiogenic agents in the maintenance treatment of ovarian cancer: a systematic review and meta-analysis with trial sequential analysis of randomized controlled trials

Background: Poly (ADP-ribose) polymerase (PARP) inhibitor and antiangiogenic agent monotherapy have shown to be effective as maintenance treatment in patients with ovarian cancer (OC). However, there is currently a lack of evidence-based study to directly compare the effects of combination therapy w...

Full description

Bibliographic Details
Main Authors: Yan Wei, Li He, Tao Liu, Tao Guo, Cong Xie, Jigang Jia, Yonghong Lin, Jiang Liu, Jiayin Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Pharmacology
Subjects:
PARP inhibitors
antiangiogenic agents
olaparib
bevacizumab
ovarian cancer
combination therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1372077/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1372077/full

Similar Items