Systems assessment of statins hazard: Integrating in silico prediction, developmental toxicity profile and transcriptomics in zebrafish

Statins are prescribed widely as lipid-lowering agents. However, statins are associated with an increased harmful risk on public health and the ecosystem. Little is known about statins’ toxicity on biological development and the underlying molecular mechanisms. We exposed zebrafish embryos to a seri...

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Bibliographic Details
Main Authors: Ying Han, Yuanyuan Ma, Junwei Tong, Jingpu Zhang, Changqin Hu
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322008211