Spatiotemporal regulation of autophagy during Caenorhabditis elegans aging

Spatiotemporal regulation of autophagy during Caenorhabditis elegans aging

Autophagy has been linked to longevity in many species, but the underlying mechanisms are unclear. Using a GFP-tagged and a new tandem-tagged Atg8/LGG-1 reporter, we quantified autophagic vesicles and performed autophagic flux assays in multiple tissues of wild-type Caenorhabditis elegans and long-l...

Full description

Bibliographic Details
Main Authors: Jessica T Chang, Caroline Kumsta, Andrew B Hellman, Linnea M Adams, Malene Hansen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-07-01
Series:eLife
Subjects:
autophagy,
Atg8/LC3
tissue-specificity
aging
daf-2
glp-1
Online Access:https://elifesciences.org/articles/18459

Internet

https://elifesciences.org/articles/18459

Similar Items