New chalcone derivatives as potential antimicrobial and antioxidant agent

Abstract Seven chalcone derivatives were synthesized by the Claisen-Schmidt condensation. The structures of the compounds were confirmed by spectral data (Ultraviolet/visible, infrared, nuclear magnetic resonance and mass spectroscopy). The compounds were tested for their in silico and in vitro anti...

Full description

Bibliographic Details
Main Authors: Emelda N. Okolo, David I. Ugwu, Benjamin E. Ezema, Joseph C. Ndefo, Florence U. Eze, Chidimma G. Ezema, James A. Ezugwu, Oguejiofo T. Ujam
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01292-5