XX sex chromosome complement modulates immune responses to heat-killed Streptococcus pneumoniae immunization in a microbiome-dependent manner

Abstract Background Differences in male vs. female immune responses are well-documented and have significant clinical implications. While the immunomodulatory effects of sex hormones are well established, the contributions of sex chromosome complement (XX vs. XY) and gut microbiome diversity on immu...

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Bibliographic Details
Main Authors: Carly J. Amato-Menker, Quinn Hopen, Andrea Pettit, Jasleen Gandhi, Gangqing Hu, Rosana Schafer, Jennifer Franko
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Biology of Sex Differences
Subjects:
Online Access:https://doi.org/10.1186/s13293-024-00597-0