CCL7 playing a dominant role in recruiting early OCPs to facilitate osteolysis at metastatic site of colorectal cancer

CCL7 playing a dominant role in recruiting early OCPs to facilitate osteolysis at metastatic site of colorectal cancer

Abstract Background Chemoattractant is critical to recruitment of osteoclast precursors and stimulates tumor bone metastasis. However, the role of chemoattractant in bone metastasis of colorectal cancer (CRC) is still unclear. Methods Histochemistry analysis and TRAP staining were utilized to detect...

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Bibliographic Details
Main Authors: He Yang, Li Jian, Qian Jin, Kang Xia, Wang Cai-ru, Sheng Jun, Huang Chen, Wang Wei, Song Ben-jing, Li Shi-hong, Long Shi-wei, Wu Juan, Zheng Wei
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cell Communication and Signaling
Subjects:
Bone metastasis
CRC
Osteoclast precursors
CCL7
CCR1
Online Access:https://doi.org/10.1186/s12964-022-00867-7

Internet

https://doi.org/10.1186/s12964-022-00867-7

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