C Type Natriuretic Peptide Receptor Activation Inhibits Sodium Channel Activity in Human Aortic Endothelial Cells by Activating the Diacylglycerol-Protein Kinase C Pathway

C Type Natriuretic Peptide Receptor Activation Inhibits Sodium Channel Activity in Human Aortic Endothelial Cells by Activating the Diacylglycerol-Protein Kinase C Pathway

The C-type natriuretic peptide receptor (NPRC) is expressed in many cell types and binds all natriuretic peptides with high affinity. Ligand binding results in the activation or inhibition of various intracellular signaling pathways. Although NPRC ligand binding has been shown to regulate various io...

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Bibliographic Details
Main Authors: Ling Yu, Mohammad-Zaman Nouri, Lauren P. Liu, Niharika Bala, Nancy D. Denslow, John F. LaDisa, Abdel A. Alli
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
natriuretic peptide receptor C
endothelial sodium channels
diacylglycerols
protein kinase C
aortic endothelial cells
Online Access:https://www.mdpi.com/1422-0067/23/22/13959

Internet

https://www.mdpi.com/1422-0067/23/22/13959

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