NPM1 GENETIC VARIANTS: THE IMPORTANCE IN THE DIAGNOSIS OF THE ACUTE MYELOID LEUKEMIA
Background: Acute Myeloid Leukemia a severe cancer of the bone marrow (BM), characterized by accumulation of leukemic blasts in the BM and peripheral blood. The development is associated with genetic changes, as the Nucleophosmin gene (NPM1), common among 20-30% of the AML cases, being recognized by...
| Format: | Article |
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| Language: | English |
| Published: |
Elsevier
2023-10-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137923007745 |