Low plasma concentrations of apolipoprotein M are associated with disease activity and endothelial dysfunction in systemic lupus erythematosus

Low plasma concentrations of apolipoprotein M are associated with disease activity and endothelial dysfunction in systemic lupus erythematosus

Abstract Background Apolipoprotein M (apoM) is a 25-kDa apolipoprotein present in 5% of high-density lipoprotein (HDL) particles. It is suggested to be anti-atherogenic and to play a key role in sustaining endothelial barrier integrity. SLE patients have increased cardiovascular disease risk, and we...

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Bibliographic Details
Main Authors: Helena Tydén, Christian Lood, Andreas Jönsen, Birgitta Gullstrand, Robin Kahn, Petrus Linge, Sunil B. Kumaraswamy, Björn Dahlbäck, Anders A. Bengtsson
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Arthritis Research & Therapy
Subjects:
Systemic lupus erythematosus
Apolipoprotein M
Disease activity
Endothelial dysfunction
Online Access:http://link.springer.com/article/10.1186/s13075-019-1890-2

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http://link.springer.com/article/10.1186/s13075-019-1890-2

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