Antimicrobial activities of pyridinium-tailored pyrazoles bearing 1,3,4-oxadiazole scaffolds

Antimicrobial activities of pyridinium-tailored pyrazoles bearing 1,3,4-oxadiazole scaffolds

Herein, a series of pyridinium-tailored 5-trifluoromethylpyrazoles containing 1,3,4-oxadiazole moieties were constructed through coupling key pharmaceutical fragments of pyridinium, pyrazole, and 1,3,4-oxadiazole scaffolds in single molecular architecture. Antimicrobial results suggested that this k...

Full description

Bibliographic Details
Main Authors: Lei Zhou, Pei-Yi Wang, Jian Zhou, Wu-Bin Shao, He-Shu Fang, Zhi-Bing Wu, Song Yang
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Journal of Saudi Chemical Society
Subjects:
5-Trifluoromethylpyrazole
Pyridinium
1,3,4-Oxadiazole
Antibacterial
Antifungal
Online Access:http://www.sciencedirect.com/science/article/pii/S131961031730056X

Internet

http://www.sciencedirect.com/science/article/pii/S131961031730056X

Similar Items