IFIT2‐depleted metastatic oral squamous cell carcinoma cells induce muscle atrophy and cancer cachexia in mice

IFIT2‐depleted metastatic oral squamous cell carcinoma cells induce muscle atrophy and cancer cachexia in mice

Abstract Background Interferon‐induced protein with tetratricopeptide repeat 2 (IFIT2) is a reported metastasis suppressor in oral squamous cell carcinoma (OSCC). Metastases and cachexia may coexist. The effect of cancer metastasis on cancer cachexia is largely unknown. We aimed to address this gap...

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Bibliographic Details
Main Authors: Kuo‐Chu Lai, Zi‐Xuan Hong, Jyh‐Gang Hsieh, Hui‐Ju Lee, Muh‐Hwa Yang, Chia‐Husu Hsieh, Cheng‐Han Yang, Yan‐Ru Chen
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Oral squamous cell carcinoma
IFIT2
Metastasis
Cachexia
Muscle atrophy
IL6
Online Access:https://doi.org/10.1002/jcsm.12943

Internet

https://doi.org/10.1002/jcsm.12943

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