Novel linkage and association of the mineralocorticoid receptor gene (NR3C2) with familial type 2 diabetes and depression and their comorbidity

Novel linkage and association of the mineralocorticoid receptor gene (NR3C2) with familial type 2 diabetes and depression and their comorbidity

Introduction: The mineralocorticoid receptor gene (NR3C2) appears to modulate stress and cognitive performance in patients with major depressive disorder (MDD). In addition, abnormalities in NR3C2 are associated in rodents with type 2 diabetes (T2D) and in humans with features of metabolic syndrome....

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Bibliographic Details
Main Authors: Mutaz Amin, Shumail Syed, Rongling Wu, Teodor T. Postolache, Claudia Gragnoli
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Aspects of Molecular Medicine
Subjects:
Nuclear receptor subfamily 3 group C member 2
NR3C2
Major depressive disorder
MDD
Type 2 diabetes
Mineralcorticoid receptor antagonist
Online Access:http://www.sciencedirect.com/science/article/pii/S2949688823000035

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http://www.sciencedirect.com/science/article/pii/S2949688823000035

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