Novel linkage and association of the mineralocorticoid receptor gene (NR3C2) with familial type 2 diabetes and depression and their comorbidity
Introduction: The mineralocorticoid receptor gene (NR3C2) appears to modulate stress and cognitive performance in patients with major depressive disorder (MDD). In addition, abnormalities in NR3C2 are associated in rodents with type 2 diabetes (T2D) and in humans with features of metabolic syndrome....
Main Authors: | Mutaz Amin, Shumail Syed, Rongling Wu, Teodor T. Postolache, Claudia Gragnoli |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-01-01
|
Series: | Aspects of Molecular Medicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2949688823000035 |
Similar Items
-
Familial Linkage and Association of the <i>NR3C1</i> Gene with Type 2 Diabetes and Depression Comorbidity
by: Mutaz Amin, et al.
Published: (2022-10-01) -
The glucocorticoid receptor gene (NR3C1) is linked to and associated with polycystic ovarian syndrome in Italian families
by: Shumail Syed, et al.
Published: (2024-01-01) -
Novel 1,4-Dihydropyridine Derivatives as Mineralocorticoid Receptor Antagonists
by: Felipe Luis Pérez-Gordillo, et al.
Published: (2023-01-01) -
Glucocorticoid receptor (NR3C1) genetic polymorphisms and the outcomes of sudden sensorineural hearing loss
by: Chen-Yu Chien, et al.
Published: (2023-02-01) -
Conditional Ablation of Glucocorticoid and Mineralocorticoid Receptors from Cochlear Supporting Cells Reveals Their Differential Roles for Hearing Sensitivity and Dynamics of Recovery from Noise-Induced Hearing Loss
by: Charles C. Barnes, et al.
Published: (2023-02-01)