MSC stimulate ovarian tumor growth during intercellular communication but reduce tumorigenicity after fusion with ovarian cancer cells

MSC stimulate ovarian tumor growth during intercellular communication but reduce tumorigenicity after fusion with ovarian cancer cells

Abstract The tumor microenvironment enables important cellular interactions between cancer cells and recruited adjacent populations including mesenchymal stroma/stem cells (MSC). In vivo cellular interactions of primary human MSC in co-culture with human SK-OV-3 ovarian cancer cells revealed an incr...

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Bibliographic Details
Main Authors: Catharina Melzer, Juliane von der Ohe, Ralf Hass
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Cell Communication and Signaling
Subjects:
Mesenchymal stem cells
Breast and ovarian cancer
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s12964-018-0279-1

Internet

http://link.springer.com/article/10.1186/s12964-018-0279-1

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