Development and Validation of an IDH1-Associated Immune Prognostic Signature for Diffuse Lower-Grade Glioma

Development and Validation of an IDH1-Associated Immune Prognostic Signature for Diffuse Lower-Grade Glioma

A mutation in the isocitrate dehydrogenase 1 (IDH1) gene is the most common mutation in diffuse lower-grade gliomas (LGGs), and it is significantly related to the prognosis of LGGs. We aimed to explore the influence of the IDH1 mutation on the immune microenvironment and develop an IDH1-associated i...

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Bibliographic Details
Main Authors: Xiangyang Deng, Dongdong Lin, Bo Chen, Xiaojia Zhang, Xingxing Xu, Zelin Yang, Xuchao Shen, Liang Yang, Xiangqi Lu, Hansong Sheng, Bo Yin, Nu Zhang, Jian Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Oncology
Subjects:
lower-grade glioma
IDH1
mutation
immune prognostic signature
nomogram
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01310/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01310/full

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