Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells

The first mouse adult-repopulating hematopoietic stem cells emerge in the aorta-gonad-mesonephros region at embryonic day (E) 10.5. Their numbers in this region increase thereafter and begin to decline at E12.5, thus pointing to the possible existence of both positive and negative regulators of emer...

Full description

Bibliographic Details
Main Authors: Bahar Mirshekar-Syahkal, Esther Haak, Gillian M. Kimber, Kevin van Leusden, Kirsty Harvey, John O'Rourke, Jorge Laborda, Steven R. Bauer, Marella F. T. R. de Bruijn, Anne C. Ferguson-Smith, Elaine Dzierzak, Katrin Ottersbach
Format: Article
Language:English
Published: Ferrata Storti Foundation 2013-02-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6551