Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs

Assessment by miRNA microarray of an autologous cancer antigen‐pulsed adoptive immune ensemble cell therapy (AC‐ACT) approach; demonstrated induction of anti‐oncogenic and anti‐PD‐L1 miRNAs

Abstract A 60‐year‐old woman with stage IV rectal cancer received adoptive cell therapy with autologous cancer antigen (AC‐ACT) causing induction of anti‐oncogenic and anti‐PD‐L1 miRNAs as assessed by miRNA microarray. More than 1 year after AC‐ACT, metastases have been arrested, and the patient rep...

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Bibliographic Details
Main Authors: Masanobu Chinami, Kaoru Iwabuchi, Yoshiteru Muto, Yasuhiko Uchida, Ryu Arita, Rana A. Shuraim, Chaker N. Adra
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Clinical Case Reports
Subjects:
adoptive cell therapy
cancer
immunotherapy
miRNA analysis
PD‐1
Online Access:https://doi.org/10.1002/ccr3.2343

Internet

https://doi.org/10.1002/ccr3.2343

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