Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice

Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice

Adipose tissue expansion occurs via enlargement of adipocytes as well as the generation of new fat cells, the latter being associated with more favorable metabolic outcomes. Here, the authors show that activation of adipocyte Piezo1 results in release of FGF1 and stimulates the differentiation of ad...

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Bibliographic Details
Main Authors: ShengPeng Wang, Shuang Cao, Malika Arhatte, Dahui Li, Yue Shi, Sabrina Kurz, Jiong Hu, Lei Wang, Jingchen Shao, Ann Atzberger, Zheng Wang, Changhe Wang, Weijin Zang, Ingrid Fleming, Nina Wettschureck, Eric Honoré, Stefan Offermanns
Format: Article
Language:English
Published: Nature Portfolio 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16026-w

Internet

https://doi.org/10.1038/s41467-020-16026-w

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