Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-Inflammatory Potential

Multidrug Resistance Modulation Activity of Silybin Derivatives and Their Anti-Inflammatory Potential

Silybin is considered to be the main biologically active component of silymarin. Its oxidized derivative 2,3-dehydrosilybin typically occurs in silymarin in small, but non-negligible amounts (up to 3%). Here, we investigated in detail complex biological activities of silybin and 2,3-dehydrosilybin o...

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Bibliographic Details
Main Authors: Simona Dobiasová, Kateřina Řehořová, Denisa Kučerová, David Biedermann, Kristýna Káňová, Lucie Petrásková, Kamila Koucká, Radka Václavíková, Kateřina Valentová, Tomáš Ruml, Tomáš Macek, Vladimír Křen, Jitka Viktorová
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Antioxidants
Subjects:
silybin
dehydrosilybin
immunomodulation
P-glycoprotein
doxorubicin resistance
cytokines
Online Access:https://www.mdpi.com/2076-3921/9/5/455

Internet

https://www.mdpi.com/2076-3921/9/5/455

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