Absence of medication-related jaw osteonecrosis after treatment with strontium ranelate in ovariectomized rats

Absence of medication-related jaw osteonecrosis after treatment with strontium ranelate in ovariectomized rats

Abstract This study aimed to evaluate the potential of strontium ranelate (SR) in medication-related jaw osteonecrosis (MRONJ) after tooth extraction in ovariectomized rats. Thirty ovariectomized rats were divided into three groups (n = 10): bisphophonate (BP) group (zoledronic acid; 0.4 mg/kg/week)...

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Main Authors: Leomar Emanuel de Almeida MECCA, Amanda Regina FISCHBORN, Jessica Daniela ANDREIS, Gabrielle DELFRATE, Tayline MROCZEK, Natália Mariane RIGO, Fábio Brasil de OLIVEIRA, Myrella Lessio CASTRO, Mario TABA JUNIOR, Marcela CLAUDINO, Gilson Cesar Nobre FRANCO
Format: Article
Language:English
Published: Sociedade Brasileira de Pesquisa Odontológica 2022-06-01
Series:Brazilian Oral Research
Subjects:
Zoledronic Acid
Bisphosphonate-Associated Osteonecrosis of The Jaw
Rats
Mandible
Strontium
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242022000100272&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242022000100272&tlng=en

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