Quantitative Detection of the Foot-And-Mouth Disease Virus Serotype O 146S Antigen for Vaccine Production Using a Double-Antibody Sandwich ELISA and Nonlinear Standard Curves.

Quantitative Detection of the Foot-And-Mouth Disease Virus Serotype O 146S Antigen for Vaccine Production Using a Double-Antibody Sandwich ELISA and Nonlinear Standard Curves.

The efficacy of an inactivated foot-and-mouth disease (FMD) vaccine is mainly dependent on the integrity of the foot-and-mouth disease virus (FMDV) particles. At present, the standard method to quantify the active component, the 146S antigen, of FMD vaccines is sucrose density gradient (SDG) analysi...

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Bibliographic Details
Main Authors: Xia Feng, Jun-Wu Ma, Shi-Qi Sun, Hui-Chen Guo, Ya-Min Yang, Ye Jin, Guang-Qing Zhou, Ji-Jun He, Jian-Hong Guo, Shu-yun Qi, Mi Lin, Hu Cai, Xiang-Tao Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4773165?pdf=render

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http://europepmc.org/articles/PMC4773165?pdf=render

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