Epstein-Barr virus but not cytomegalovirus is associated with reduced vaccine antibody responses in Gambian infants.

BACKGROUND:Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are persistent herpesviruses that have various immunomodulatory effects on their hosts. Both viruses are usually acquired in infancy in Sub-Saharan Africa, a region where childhood vaccines are less effective than in high income settings....

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Bibliographic Details
Main Authors: Beth Holder, David J C Miles, Steve Kaye, Sarah Crozier, Nuredin Ibrahim Mohammed, Nancy O Duah, Elishia Roberts, Olubukola Ojuola, Melba S Palmero, Ebrima S Touray, Pauline Waight, Matthew Cotten, Sarah Rowland-Jones, Marianne van der Sande, Hilton Whittle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2984441?pdf=render