Integrated Intensified Chemoradiation in the Setting of Total Neoadjuvant Therapy (TNT) in Patients with Locally Advanced Rectal Cancer: A Retrospective Single-Arm Study on Feasibility and Efficacy

Integrated Intensified Chemoradiation in the Setting of Total Neoadjuvant Therapy (TNT) in Patients with Locally Advanced Rectal Cancer: A Retrospective Single-Arm Study on Feasibility and Efficacy

While surgery is considered the main treatment for early-stage rectal cancer, locally advanced rectal cancer needs to be handled with a multidisciplinary approach. Based on literature data suggesting promising advantages of total neoadjuvant therapy (TNT), we performed a retrospective, single-arm, s...

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Bibliographic Details
Main Authors: Maria Chiara Lo Greco, Madalina La Rocca, Giorgia Marano, Irene Finocchiaro, Rocco Luca Emanuele Liardo, Roberto Milazzotto, Grazia Acquaviva, Antonello Basile, Stefano Palmucci, Pietro Valerio Foti, Stefano Pergolizzi, Antonio Pontoriero, Silvana Parisi, Corrado Spatola
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
locally advanced rectal cancer
total neoadjuvant therapy
long course radiotherapy
chemoradiotherapy
conventionally fractionated radiotherapy
hypofractionated radiotherapy
Online Access:https://www.mdpi.com/2072-6694/15/3/921

Internet

https://www.mdpi.com/2072-6694/15/3/921

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