Navigating the Nose-to-Brain Route: A Systematic Review on Lipid-Based Nanocarriers for Central Nervous System Disorders

Navigating the Nose-to-Brain Route: A Systematic Review on Lipid-Based Nanocarriers for Central Nervous System Disorders

Background: The blood–brain barrier (BBB) regulates brain substance entry, posing challenges for treating brain diseases. Traditional methods face limitations, leading to the exploration of non-invasive intranasal drug delivery. This approach exploits the direct nose-to-brain connection, overcoming...

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Bibliographic Details
Main Authors: Edoardo Agosti, Marco Zeppieri, Sara Antonietti, Luigi Battaglia, Tamara Ius, Caterina Gagliano, Marco Maria Fontanella, Pier Paolo Panciani
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pharmaceutics
Subjects:
neurodegenerative disorders
neuro-oncological diseases
blood–brain barrier
lipid nanoparticles
intranasal administration
clinical outcomes
Online Access:https://www.mdpi.com/1999-4923/16/3/329

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https://www.mdpi.com/1999-4923/16/3/329

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