The Uridylyl Transferase TUT7‐Mediated Accumulation of Exosomal miR‐1246 Reprograms TAMs to Support CRC Progression

The Uridylyl Transferase TUT7‐Mediated Accumulation of Exosomal miR‐1246 Reprograms TAMs to Support CRC Progression

Abstract Tumor‐associated macrophages (TAMs) play a crucial role in promoting tumor growth and dissemination, motivating a search for key targets to interfere with the activation of TAMs or reprogram TAMs into the tumor‐suppressive type. To gain insight into the mechanisms of macrophage polarization...

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Bibliographic Details
Main Authors: Yifei Feng, Chi Jin, Tuo Wang, Zhihao Chen, Dongjian Ji, Yue Zhang, Chuan Zhang, Dongsheng Zhang, Wen Peng, Yueming Sun
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
colorectal cancer
exosomes
NLRP3
tumor‐associated macrophages
TUT7
Online Access:https://doi.org/10.1002/advs.202304222

Internet

https://doi.org/10.1002/advs.202304222

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