A viral fusogen hijacks the actin cytoskeleton to drive cell-cell fusion

Cell-cell fusion, which is essential for tissue development and used by some viruses to form pathological syncytia, is typically driven by fusogenic membrane proteins with tall (>10 nm) ectodomains that undergo conformational changes to bring apposing membranes in close contact prior to fusio...

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Bibliographic Details
Main Authors: Ka Man Carmen Chan, Sungmin Son, Eva M Schmid, Daniel A Fletcher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/51358