Silymarin induces insulin resistance through an increase of phosphatase and tensin homolog in Wistar rats.

Silymarin induces insulin resistance through an increase of phosphatase and tensin homolog in Wistar rats.

BACKGROUND AND AIMS: Phosphatase and tensin homolog (PTEN) is a phosphoinositide phosphatase that regulates crucial cellular functions, including insulin signaling, lipid and glucose metabolism, as well as survival and apoptosis. Silymarin is the active ingredient in milk thistle and exerts numerous...

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Bibliographic Details
Main Authors: Kai-Chun Cheng, Akihiro Asakawa, Ying-Xiao Li, Hsien-Hui Chung, Haruka Amitani, Takatoshi Ueki, Juei-Tang Cheng, Akio Inui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3880317?pdf=render

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http://europepmc.org/articles/PMC3880317?pdf=render

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