Unraveling the Molecular Basis of the Dystrophic Process in Limb-Girdle Muscular Dystrophy LGMD-R12 by Differential Gene Expression Profiles in Diseased and Healthy Muscles

Unraveling the Molecular Basis of the Dystrophic Process in Limb-Girdle Muscular Dystrophy LGMD-R12 by Differential Gene Expression Profiles in Diseased and Healthy Muscles

Limb-girdle muscular dystrophy R12 (LGMD-R12) is caused by two mutations in anoctamin-5 (<i>ANO5</i>). Our aim was to identify genes and pathways that underlie LGMD-R12 and explain differences in the molecular predisposition and susceptibility between three thigh muscles that are severel...

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Bibliographic Details
Main Authors: Christophe E. Depuydt, Veerle Goosens, Rekin’s Janky, Ann D’Hondt, Jan L. De Bleecker, Nathalie Noppe, Stefaan Derveaux, Dietmar R. Thal, Kristl G. Claeys
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
anoctamin-5
<i>ANO5</i>
LGMD2L
muscle dystrophy
RNA-seq
transcriptomics
Online Access:https://www.mdpi.com/2073-4409/11/9/1508

Internet

https://www.mdpi.com/2073-4409/11/9/1508

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