Raltegravir cerebrospinal fluid concentrations in HIV-1 infection.

Raltegravir is an HIV-1 integrase inhibitor currently used in treatment-experienced HIV-1-infected patients resistant to other drug classes. In order to assess its central nervous system penetration, we measured raltegravir concentrations in cerebrospinal fluid (CSF) and plasma in subjects receiving...

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Bibliographic Details
Main Authors: Aylin Yilmaz, Magnus Gisslén, Serena Spudich, Evelyn Lee, Anura Jayewardene, Francesca Aweeka, Richard W Price
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2731205?pdf=render