The mammalian target of rapamycin contributes to synovial fibroblast pathogenicity in rheumatoid arthritis

The mammalian target of rapamycin contributes to synovial fibroblast pathogenicity in rheumatoid arthritis

ObjectivesThe mammalian target of Rapamycin (mTOR) is a metabolic master regulator of both innate and adaptive immunity; however, its exact role in stromal cell biology is unknown. In this study we explored the role of the mTOR pathway on Rheumatoid Arthritis synovial fibroblast (RASF) metabolism an...

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Príomhchruthaitheoirí: Brianne E. Barker, Megan M. Hanlon, Viviana Marzaioli, Conor M. Smith, Clare C. Cunningham, Jean M. Fletcher, Douglas J. Veale, Ursula Fearon, Mary Canavan
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Frontiers Media S.A. 2023-02-01
Sraith:Frontiers in Medicine
Ábhair:
rheumatoid arthritis
synovial fibroblast
mTOR
hippo-YAP
yes associated protein
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fmed.2023.1029021/full

Ar líne

https://www.frontiersin.org/articles/10.3389/fmed.2023.1029021/full

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