Tumor-Derived Extracellular Vesicles Require β1 Integrins to Promote Anchorage-Independent Growth

Tumor-Derived Extracellular Vesicles Require β1 Integrins to Promote Anchorage-Independent Growth

Summary: The β1 integrins, known to promote cancer progression, are abundant in extracellular vesicles (EVs). We investigated whether prostate cancer (PrCa) EVs affect anchorage-independent growth and whether β1 integrins are required for this effect. Specifically using a cell-line-based genetic res...

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Detalhes bibliográficos
Main Authors: Rachel M. DeRita, Aejaz Sayeed, Vaughn Garcia, Shiv Ram Krishn, Christopher D. Shields, Srawasti Sarker, Andrea Friedman, Peter McCue, Sudheer Kumar Molugu, Ulrich Rodeck, Adam P. Dicker, Lucia R. Languino
Formato: Artigo
Idioma:English
Publicado em: Elsevier 2019-04-01
Colecção:iScience
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004219300884

Internet

http://www.sciencedirect.com/science/article/pii/S2589004219300884

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