Hyperpolarized <sup>13</sup>C Magnetic Resonance Spectroscopic Imaging of Pyruvate Metabolism in Murine Breast Cancer Models of Different Metastatic Potential

Hyperpolarized <sup>13</sup>C Magnetic Resonance Spectroscopic Imaging of Pyruvate Metabolism in Murine Breast Cancer Models of Different Metastatic Potential

This study uses dynamic hyperpolarized [1-<sup>13</sup>C]pyruvate magnetic resonance spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between highly metastatic (4T1, <i>n</i> = 7) and metastatically dormant (4T07, <i>n</i> = 7) murine...

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Bibliographic Details
Main Authors: Erin B. Macdonald, Paul Begovatz, Gregory P. Barton, Sarah Erickson-Bhatt, David R. Inman, Benjamin L. Cox, Kevin W. Eliceiri, Roberta M. Strigel, Suzanne M. Ponik, Sean B. Fain
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Metabolites
Subjects:
breast cancer
metastatic potential
metabolism
MRSI
hyperpolarized
carbon-13
Online Access:https://www.mdpi.com/2218-1989/11/5/274

Internet

https://www.mdpi.com/2218-1989/11/5/274

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