Effects of Hydroxypropyl-Beta-Cyclodextrin on Cultured Brain Endothelial Cells

Effects of Hydroxypropyl-Beta-Cyclodextrin on Cultured Brain Endothelial Cells

The application of 2-hydroxypropyl-beta-cyclodextrin (HPBCD) in the treatment of the rare cholesterol and lipid storage disorder Niemann–Pick disease type C opened new perspectives in the development of an efficient therapy. Even if the systemic administration of HPBCD was found to be effective, its...

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Bibliographic Details
Main Authors: Szilvia Veszelka, Mária Mészáros, Gergő Porkoláb, Ágnes Rusznyák, Katalin Szászné Réti-Nagy, Mária A. Deli, Miklós Vecsernyés, Ildikó Bácskay, Judit Váradi, Ferenc Fenyvesi
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
blood–brain barrier
2-hydroxypropyl-beta-cyclodextrin
endocytosis
Niemann–Pick disease
type C
Online Access:https://www.mdpi.com/1420-3049/27/22/7738

Internet

https://www.mdpi.com/1420-3049/27/22/7738

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