Prominin‐1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice

Prominin‐1 deletion results in spermatogenic impairment, sperm morphological defects, and infertility in mice

Abstract Purpose Spermatogenesis is a complex process orchestrated by several essential genes. Prominin‐1 (Prom1/PROM1) is a gene that is expressed in the testis but with a poorly understood role in spermatogenesis. Methods We used Prom1 knockout (Prom1 KO) mice to assess the role of Prom1 in sperma...

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Bibliographic Details
Main Authors: Haruka Matsukuma, Yuka Kobayashi, Shintaro Oka, Fumiaki Higashijima, Kazuhiro Kimura, Erika Yoshihara, Noriaki Sasai, Koji Shiraishi
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Reproductive Medicine and Biology
Subjects:
flagellum function
Prom1 KO mice
Prominin‐1
sperm morphology
spermatogenesis
Online Access:https://doi.org/10.1002/rmb2.12514

Internet

https://doi.org/10.1002/rmb2.12514

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