Evaluation of a Four-Gene Panel for Hereditary Cancer Risk Assessment

Evaluation of a Four-Gene Panel for Hereditary Cancer Risk Assessment

<i>BRCA1</i>/<i>2</i> are tumor suppressor genes involved in DNA double-strand break repair. They are the most penetrant genes for hereditary breast and ovarian cancers, but pathogenic variants in these two genes can be identified only in a fraction of hereditary cases. Follo...

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Bibliographic Details
Main Authors: Angela Secondino, Flavio Starnone, Iolanda Veneruso, Maria Antonietta Di Tella, Serena Conato, Carmine De Angelis, Sabino De Placido, Valeria D’Argenio
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Genes
Subjects:
breast cancer
ovarian cancer
<i>BRCA1</i>
<i>BRCA2</i>
<i>CHEK2</i>
<i>PALB2</i>
Online Access:https://www.mdpi.com/2073-4425/13/4/682

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https://www.mdpi.com/2073-4425/13/4/682

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